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U.S. Licensed Pharmacies
Licensed Providers in all 50 States
Free Expedited Shipment
U.S. Licensed Pharmacies
Licensed Providers in all 50 States
Free Expedited Shipment
U.S. Licensed Pharmacies
Licensed Providers in all 50 States
Free Expedited Shipment
U.S. Licensed Pharmacies
Licensed Providers in all 50 States
Free Expedited Shipment
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Safety Information

Last Updated: September 1, 2025

Important Safety Information Regarding Compounded NAD+

Compounded Medication Disclaimer

Compounded medications, including NAD+ (nicotinamide adenine dinucleotide), are not approved by the U.S. Food and Drug Administration (FDA) and do not undergo the same clinical studies as FDA-approved drugs to evaluate safety or efficacy. Compounded medications may still be legally prescribed when determined appropriate by a licensed healthcare provider following a medical consultation.

Eligibility

NAD+ treatment may be considered for adults experiencing symptoms such as fatigue, low energy, cognitive decline, or those seeking longevity-focused support. Eligibility is determined on a case-by-case basis. A licensed healthcare provider will review your intake to confirm eligibility and ensure treatment is safe and appropriate for you.

Indication

NAD+ is a vital coenzyme found in every cell of the body. It is essential for energy production, mitochondrial function, and DNA repair. Supplementation with compounded NAD+ aims to support cellular energy, metabolism, brain health, and healthy aging.

Contraindications

Do not use NAD+ treatment if you:

  • Have a known hypersensitivity to NAD+ or any excipients in the formulation.
  • Are pregnant or breastfeeding.

Warnings and Precautions

Potential risks and side effects include:

  • Injection site reactions: Pain, redness, or swelling.
  • Digestive discomfort: Nausea, cramping, or bloating.
  • Flushing or warmth: Mild flushing may occur with NAD+ administration.
  • Allergic reactions: Rare, but possible. Seek medical help if you experience rash, difficulty breathing, or swelling.

Precautions Before Use

Inform your healthcare provider if you:

  • Have a history of cardiovascular disease, diabetes, or kidney disorders.
  • Are pregnant, planning pregnancy, or breastfeeding.
  • Are taking other medications, including prescriptions, over-the-counter drugs, vitamins, or supplements.

Administration

  • NAD+ is administered by subcutaneous injection.
  • Follow the dosing instructions provided by your healthcare provider.
  • Do not adjust or discontinue NAD+ without consulting your provider.

Common Side Effects

The most common side effects include:

  • Mild injection site irritation.
  • Nausea or stomach discomfort.
  • Headache or dizziness.

This list does not include all possible side effects. Consult your healthcare provider regarding any adverse effects you may experience.

Important Notes

  • NAD+ treatment should only be initiated and monitored by a licensed healthcare provider.
  • If you experience a medical emergency, call 911 immediately.
  • For additional safety information, contact FDA MedWatch at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

Commitment to Safety

Yücca Health is committed to providing safe, transparent, and high-quality care. We encourage patients to discuss all concerns openly with their provider to ensure the best possible treatment outcomes.