Frequently Asked Questions.
Getting Started
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Four steps:
Complete the intake — 2 to 5 minutes, depending on your health history. Questions about your health, current medications, and goals.
A clinician reviews it — typically within 24 hours. They may message you for more detail.
If prescribed, the pharmacy prepares your medication — usually 2 to 3 business days.
It ships to you — expedited 2-day shipping, free.
You’re only charged after a clinician approves your treatment. A temporary authorization hold appears at checkout and is released if no prescription is written.
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No, and we wouldn’t want to promise that. A clinician decides whether treatment is appropriate based on your health history and what you tell them during intake. Some people aren’t candidates, and some are better served by a different treatment.
If a clinician declines to prescribe, you get a full refund — including the consultation fee. Automatically, without having to ask.
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Eligibility is a clinical decision made by your provider, based on your full medical history, current medications, and health goals — not a number on a form.
Clinicians generally follow published guidance for the use of GLP-1 medications in weight management, which considers body mass index alongside weight-related health conditions. But BMI alone doesn’t determine whether treatment is appropriate for you, and the honest answer is that we can’t tell you before a clinician reviews your intake.
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Usually not. Most patients complete everything online.
Your clinician may request lab results or additional information if it’s clinically needed for your situation. If that applies to you, they’ll tell you what’s required.
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All 50 U.S. states. Your clinician must be licensed in the state where you’re located, and availability can depend on your state’s telehealth rules. We ship within the United States only.
The 6-Month Promise
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If you complete six continuous months of GLP-1 injectable treatment as prescribed and haven’t lost weight compared with your logged starting weight, we refund everything you paid us over those six months — medication, consultation fees, and plan fees. There’s nothing to send back.
It’s our commitment that six months of treatment shouldn’t cost you anything if it doesn’t work for you.
It is not a medical guarantee. We’re not promising you’ll lose weight, and individual results vary. Your clinician’s guidance always comes first.
It applies to GLP-1 injectable plans started on or after September 18, 2026.
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Five things, and they matter — this only works if the record shows what actually happened:
Log your starting weight before your first shipment arrives, or within 7 days of delivery
Stay on an active plan for the full six months — without pausing, since a break ends eligibility
Take each dose on the schedule your clinician set
Confirm each dose in your portal within 72 hours
Log your weight weekly — at least 20 of the 26 weeks, no gap longer than three weeks, plus a final weigh-in at your six-month mark
Then submit your claim within 30 days of that six-month mark.
One thing to know up front: portal entries close about a week after the date they cover, so they can’t be filled in later. Logging as you go is what makes this work, and we’ll send reminders.
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It applies to GLP-1 injectable weight loss plans only — not NAD+, sermorelin, or other treatments.
It applies to plans started on or after September 18, 2026. If you enrolled before that, it doesn’t cover that enrollment.
One claim per person. Pausing, cancelling, or letting a plan lapse ends eligibility, and so does missing the logging requirements. Claiming the refund also ends your locked price.
And to be plain about something: never stay on a medication just to protect a refund. If your clinician recommends stopping or changing your treatment, do that.
Billing & Plans
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You choose your plan at checkout: monthly, 3-month, or 6-month. You’re only charged after a clinician reviews your information and issues a prescription. A temporary authorization hold appears at checkout and is released by your bank, typically within 3 to 7 business days, if no prescription is written.
Plans renew automatically at the interval you chose until you pause or cancel. We send a reminder before each renewal.
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After clinician approval, not at checkout. What you see at checkout is an authorization hold confirming the payment method, not a charge.
For renewals, we begin processing several days ahead of your delivery date so there’s time for clinician review, compounding, and shipping.
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No. Your price stays the same at every dose level for as long as your enrollment stays active.
If you enrolled at a locked price, that price holds for that medication and billing plan, including as your dose is titrated upward.
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No. We’re cash-pay and we don’t bill insurance, Medicare, or Medicaid. Many patients use HSA or FSA funds — whether that’s eligible depends on your plan administrator, so ask them before you pay.
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Yes. Buy Now, Pay Later is available at checkout, which lets you spread payments over time. Those terms come from the payment provider and are separate from your Yucca Health plan — installments don’t change the length of your plan commitment.
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Charges happen after a clinician issues your prescription, which is before the pharmacy compounds and ships. So there’s a normal gap of a few days between the charge and the delivery.
If you were charged and don’t have a prescription, or you see a duplicate charge, contact us with the date and the last four digits of the card. Confirmed billing errors are refunded the same business day in most cases.
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Yes — the Yucca 6-Month Promise. If you complete six continuous months of GLP-1 injectable treatment as prescribed and haven’t lost weight, we refund everything you paid us over those six months.
Dosing & Taking It
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Follow the instructions on your prescription label and the directions that came with your medication. They’re specific to your prescription and your concentration.
Milligrams and syringe units are not the same thing. Do not convert between them yourself, do not use a dose chart you found online, and do not follow instructions written for someone else’s prescription — concentrations differ between preparations, and a conversion error can mean a serious overdose.
If anything about your dose is unclear, do not inject. Contact us or the dispensing pharmacy first. We’d much rather answer the question than have you guess.
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Your medication arrives with an injection kit and written directions. Weight management medications are injected once weekly under the skin of the stomach, thigh, or upper arm. Sermorelin and NAD+ have their own schedules set by your clinician.
If you’re nervous about the first one, that’s normal. Message your care team and they’ll walk you through it.
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Use the instructions that came with the new prescription, not the old ones. Concentration can change when your dose changes, which means the number of syringe units can change even when the milligrams follow the schedule you expected.
If the new label doesn’t match what you were expecting, stop and ask before injecting.
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Contact your care team rather than doubling up or guessing at timing. The right answer depends on how long it’s been and where you are in your schedule.
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Follow the storage instructions from the dispensing pharmacy — they’re specific to your preparation. Medications requiring refrigeration should be refrigerated on arrival and never frozen.
If your medication arrives warm, or you notice cloudiness, particles, discoloration, or a damaged seal, do not use it. Contact us and the dispensing pharmacy.
Treatments
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GLP-1 is a hormone your body releases after you eat. It signals fullness to your brain and slows how quickly food leaves your stomach — but it clears from your system within minutes.
GLP-1 medications are built to do the same job and stay active far longer, so the fullness signal holds instead of fading between meals. They’re prescribed as once-weekly injections you give yourself at home.
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Semaglutide activates one receptor: GLP-1. Tirzepatide activates two: GLP-1 and GIP. GIP is a second fullness hormone your gut releases after eating, and it amplifies what GLP-1 is already doing.
That difference doesn’t tell you which one is right for you. Your clinician considers your medical history, your current medications, what you’ve tried before, and how you respond. Either may be appropriate, and neither is universally better.
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No. The medications prescribed through Yucca Health are compounded preparations, and compounded medications are not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness, or manufacturing quality before they’re marketed.
A compounded preparation is made by a licensed pharmacy for an individual patient, pursuant to a prescription from a clinician who has determined a compounded preparation is appropriate for that patient.
A compounded preparation is not the same as, and is not a substitute for, any FDA-approved product. We make no claim that it is equivalent in safety, effectiveness, or quality.
Talk to your clinician about the risks, benefits, and alternatives — including FDA-approved options — before starting.
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We don’t know, and anyone who tells you a number for your specific case is guessing. Individual response varies with dose, how consistently you take the medication, diet, activity, and individual biology.
What we can tell you is what the published research on the branded, FDA-approved medications shows:
In a 68-week trial of branded semaglutide 2.4 mg in 1,961 adults, average weight change was −14.9%, compared with −2.4% on placebo.
In a 72-week trial of branded tirzepatide in 2,539 adults, average weight reductions were −15.0%, −19.5% and −20.9% at the 5 mg, 10 mg and 15 mg doses, compared with −3.1% on placebo.
Those trials studied FDA-approved finished drugs, not compounded preparations, and they don’t predict your individual result. Your clinician can talk through what’s realistic for you.
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That’s a clinical decision, and it’s worth discussing with your clinician early rather than at the six-month mark.
Weight regain after stopping is common, which is why maintenance planning matters. Your treatment plan and your billing plan are separate things — review both before changing either.
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Tell your clinician. There’s usually something to adjust — dose, timing, or how side effects are being managed — and that conversation is more useful than stopping without one.
Don’t increase your dose on your own. If a change to your plan means a change to your billing, contact us and we’ll sort it out.
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The largest published weight-management trial of branded semaglutide studied 1,961 adults over 68 weeks at a 2.4 mg weekly dose. Average weight change was −14.9%, compared with −2.4% on placebo.
A separate cardiovascular outcomes trial studied branded semaglutide 2.4 mg in adults aged 45 and older with established cardiovascular disease and overweight or obesity, without diabetes. Major cardiovascular events occurred in 6.5% of the semaglutide group versus 8.0% on placebo.
Both studied FDA-approved finished drugs, not compounded preparations. They don’t establish outcomes for compounded semaglutide, and they don’t predict your individual result.
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As a once-weekly subcutaneous injection, starting low and increasing gradually so your body adjusts. A standard schedule holds each dose level for at least four weeks before stepping up.
Your clinician sets your schedule and may keep you at a level longer based on how you respond. Many patients stay below the maximum dose, and that’s a normal outcome rather than a shortfall.
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The largest published weight-management trial of branded tirzepatide studied 2,539 adults over 72 weeks. Average weight reductions were −15.0%, −19.5% and −20.9% at the 5 mg, 10 mg and 15 mg weekly doses, compared with −3.1% on placebo.
That trial studied an FDA-approved finished drug, not a compounded preparation. It doesn’t establish outcomes for compounded tirzepatide, and it doesn’t predict your individual result. Your own dose, tolerance and response will shape what happens for you.
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As a once-weekly subcutaneous injection, starting low and increasing gradually. A standard schedule holds each level for at least four weeks.
Your clinician sets the pace and may keep you at a dose longer depending on how you respond and tolerate it. Many patients stay below the maximum dose.
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NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell in your body. Its central role is helping convert the food you eat into the energy your cells run on — your mitochondria can’t complete that process without it. The same supply is used by enzymes involved in routine cell maintenance, including DNA repair.
NAD+ levels are understood to decline with age. An injection delivers the coenzyme directly, skipping digestion.
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Honestly: it varies, and some people notice little. NAD+ is not a treatment with a defined endpoint you reach — your cells consume and rebuild it continuously, so it’s ongoing support rather than a course that finishes.
The research on NAD+ supplementation in humans is still developing, and it’s less established than the evidence base behind GLP-1 medications. We’re not going to tell you it will make you feel a particular way. Your clinician can talk through what’s reasonable to expect for your situation.
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No. Compounded NAD+ is not FDA-approved, and the FDA does not review compounded preparations for safety, effectiveness, or manufacturing quality before they’re marketed. It’s prescribed by a licensed clinician and prepared by a licensed pharmacy when determined appropriate for you.
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NAD+ may be considered for adults interested in longevity-focused support. Eligibility is determined case by case by a licensed clinician.
The most common side effects are injection-site reactions, digestive discomfort, flushing or warmth, and headache. Allergic reactions are rare but possible. Tell your clinician if you have cardiovascular disease, diabetes, or kidney disorders, or if you’re pregnant, planning pregnancy, or breastfeeding.
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Sermorelin is a synthetic analog of GHRH — growth hormone-releasing hormone, the signal your hypothalamus sends to your pituitary gland. Rather than replacing growth hormone, it adds to that signal, so the hormone released is your own.
Growth hormone arrives in pulses rather than at a steady level, and the largest pulse comes during deep sleep. That’s why sermorelin is typically dosed at bedtime.
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Response varies, and we’d rather be straight with you than promise something specific. The human evidence base for sermorelin in healthy adults is limited compared with better-studied treatments, and individual results differ.
Your clinician can discuss what’s reasonable for your situation, what to watch for, and how to tell whether it’s working for you.
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No. Compounded sermorelin is not FDA-approved, and the FDA does not review compounded preparations for safety, effectiveness, or manufacturing quality before they’re marketed.
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Do not use sermorelin if you have a known hypersensitivity to it or its components, have active cancer or evidence of tumor growth, or are pregnant or breastfeeding.
Tell your clinician if you have a history of cancer — particularly hormone-sensitive cancers — or any endocrine or pituitary disorder. Sermorelin may accelerate the growth of pre-existing tumors.
Common side effects include injection-site reactions, headache, flushing, dizziness, and mild stomach upset.
Safety & Side Effects
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For GLP-1 weight management medications, the most common are gastrointestinal: nausea, diarrhea, constipation, vomiting, and abdominal discomfort. These are most common early and while your dose is increasing.
Headache, fatigue, and dizziness can also occur.
This isn’t a complete list. Tell your clinician about anything persistent or concerning — there’s usually something that can be adjusted.
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Serious risks associated with GLP-1 medications include pancreatitis, gallbladder disease, kidney injury, severe gastrointestinal problems, low blood sugar (particularly alongside insulin or sulfonylureas), and serious allergic reactions.
Branded semaglutide and tirzepatide carry a boxed warning about thyroid C-cell tumors observed in rodents; whether this applies to humans is unknown.
Seek immediate medical attention for severe abdominal pain, persistent vomiting, difficulty breathing, swelling of the face or throat, or signs of a severe allergic reaction. For an emergency, call 911.
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Do not take semaglutide or tirzepatide if you or a family member has had medullary thyroid carcinoma, if you have Multiple Endocrine Neoplasia syndrome type 2, or if you’ve had a serious allergic reaction to the medication or its ingredients.
Other conditions may make treatment inappropriate or require caution. Tell your clinician about your full medical history, all medications and supplements you take, whether you’re pregnant, planning pregnancy, or breastfeeding, and any planned procedure or surgery.
Don’t use an FAQ to decide whether you’re eligible. That’s what the clinical review is for.
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Tell your clinician about everything you take, including over-the-counter medications and supplements. Combining GLP-1 medications with insulin or sulfonylureas can increase the risk of low blood sugar, and your prescriber may need to adjust your other medications or monitoring.
Never adjust insulin or any other medication on your own.
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Weight management treatment should not be used during pregnancy. Contact your clinician promptly if you become pregnant or are planning to.
Breastfeeding requires a discussion specific to your medication — recommendations differ by product.
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Message your care team through the patient portal. For anything severe — severe abdominal pain, persistent vomiting, signs of an allergic reaction, difficulty breathing — seek immediate medical care or call 911. Don’t use messaging to report an emergency.
Shipping & Delivery
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Once a clinician approves, the pharmacy typically compounds and ships within 2 to 3 business days, via expedited 2-day service. Most patients receive their medication within a few days of approval.
Tracking is emailed when your order ships and usually activates within 24 hours.
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No. Orders ship Monday through Friday, excluding U.S. federal holidays, so temperature-sensitive shipments aren’t sitting in transit over a non-delivery day.
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Contact us within 48 hours so we can open a trace with the carrier. We’ll usually need a missing-package claim, and if theft is suspected, a police report number.
Once a carrier confirms delivery to the address on file, the loss sits with the carrier rather than with us — but we’ll help you work through their claim process.
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Photograph it before opening anything further and contact us within 48 hours. Keep the original packaging until the claim is resolved. Once verified, you’ll choose between a free replacement or a refund.
Refunds & Cancellations
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Yes, any time. Cancellation stops future charges. To stop your next renewal, cancel at least 7 days before your renewal date — we begin processing renewals several days ahead so there’s time for clinician review, compounding, and shipping.
Cancelling doesn’t refund charges already processed or orders already in progress.
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Yes, and it’s often the better option. Pausing stops charges indefinitely and keeps your locked price, where cancelling ends that price permanently.
One thing to know: if you’re enrolled under the 6-Month Promise, pausing ends your eligibility for it, because the Promise depends on six continuous months of treatment.
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Full refund: if a clinician declines to prescribe (including the consultation fee), if you cancel before your prescription is issued, if you’re charged twice, or if a pricing error on our end overcharged you.
Replacement or refund: if your medication arrives damaged, or the pharmacy confirms its integrity is compromised.
No refund: once a clinician has issued your prescription.
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Compounded medication is prepared for one specific patient at a specific dose. Once a prescription is written and tied to that preparation, federal and state pharmacy law don’t allow it to be returned, resold, or dispensed to anyone else — even if it was never opened, never shipped, or never left the pharmacy.
It isn’t a company policy we can make exceptions to.
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We review requests in the order they arrive, typically within 2 to 4 business days, faster for clear-cut cases like medical ineligibility. Approved refunds go back to the original payment method and banks typically post them in 5 to 10 business days.
About Yucca Health
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Yes. Yucca Health is a telehealth platform. Every prescription is written by a licensed clinician authorized to practice in your state, and every medication is dispensed by a licensed U.S. pharmacy. We’re LegitScript certified, and more than 1,000 patients have reviewed us on Trustpilot, where we hold a 4.6 “Excellent” rating.
We don’t practice medicine or operate a pharmacy ourselves — we handle the technology, coordination, and support that connects you to clinicians and pharmacies who do.
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Yes. Your medication is compounded and dispensed by a licensed U.S. pharmacy, and it arrives with a prescription label showing the dispensing pharmacy, the drug, the concentration, and your dosing instructions.
Compounded medications are not FDA-approved, and we say that plainly everywhere on this site. What that means is that the FDA doesn’t review compounded preparations before they’re marketed. It doesn’t mean the medication is unregulated — compounding pharmacies are licensed and inspected by state boards of pharmacy and operate under federal and state requirements.
If anything about your label or your medication looks wrong, don’t use it. Contact us and the dispensing pharmacy right away.
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Price alone doesn’t tell you much either way, so here’s the actual reason: we’re cash-pay, we don’t bill insurance, and compounded preparations cost less to produce than branded finished drugs. There’s no insurance administration in the middle.
What you should compare is what’s included, what you’re committing to, and who’s behind the care. Our plans include the provider consultation, the medication if prescribed, the injection kit, shipping, and ongoing provider messaging, with no separate consultation fee.
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Clinicians are licensed healthcare professionals authorized to practice in the state where you live, engaged through provider organizations we partner with. Prescriptions are dispensed by licensed U.S. pharmacies.
The specific clinician and pharmacy handling your care are shown in your patient portal once your order is processed, and the dispensing pharmacy’s details appear on your prescription label.
You’re never required to use a clinician or pharmacy we work with. If you’d prefer your prescription go elsewhere, tell us and we’ll accommodate that where we can.
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We built and run the platform: the intake, the patient portal, scheduling, payment, coordination with the pharmacy, shipping logistics, and non-clinical support.
We don’t make clinical decisions. Whether treatment is appropriate for you, which medication, and at what dose are decisions made independently by your clinician. We don’t influence those decisions and we don’t employ the clinicians who make them.
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Four, across two categories:
Weight management — compounded semaglutide and compounded tirzepatide, both once-weekly injections.
Longevity and recovery — NAD+ and sermorelin, both subcutaneous injections.
Each is prescription-only and requires a clinician to determine it’s appropriate for you.
Account & Privacy
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Through the patient portal, which is the right place for anything about your treatment. You can also reach support by phone or email for account, billing, and shipping questions.
Portal access doesn’t mean an immediate reply. For an emergency, call 911 rather than sending a message.
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Information about your care is protected health information, handled under federal and state health privacy law by the clinicians and pharmacies responsible for your care.
Information we collect through our website and portal is described in our Privacy Policy, and you can control how it’s used through the “Your Privacy Choices” link at the bottom of any page.