GLP-1 Weight Loss
treatment that works

GLP-1 is a hormone your body releases after you eat. It signals fullness to your brain and slows how quickly food leaves your stomach — but it clears from your system within minutes.

GLP-1 medications are built to do the same job and stay active far longer, so the fullness signal holds instead of fading between meals. They’re prescribed as once-weekly injections you give yourself at home.

See how semaglutide works See how tirzepatide works

Semaglutide activates one receptor: GLP-1. Tirzepatide activates two: GLP-1 and GIP. GIP is a second fullness hormone your gut releases after eating, and it amplifies what GLP-1 is already doing.

That difference doesn’t tell you which one is right for you. Your clinician considers your medical history, your current medications, what you’ve tried before, and how you respond. Either may be appropriate, and neither is universally better.

Compare semaglutide Compare tirzepatide Start your intake

Eligibility is a clinical decision made by your provider, based on your full medical history, current medications, and health goals — not a number on a form.

Clinicians generally follow published guidance for the use of GLP-1 medications in weight management, which considers body mass index alongside weight-related health conditions. But BMI alone doesn’t determine whether treatment is appropriate for you, and the honest answer is that we can’t tell you before a clinician reviews your intake.

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No. The medications prescribed through Yucca Health are compounded preparations, and compounded medications are not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness, or manufacturing quality before they’re marketed.

A compounded preparation is made by a licensed pharmacy for an individual patient, pursuant to a prescription from a clinician who has determined a compounded preparation is appropriate for that patient.

A compounded preparation is not the same as, and is not a substitute for, any FDA-approved product. We make no claim that it is equivalent in safety, effectiveness, or quality.

Talk to your clinician about the risks, benefits, and alternatives — including FDA-approved options — before starting.

Read full safety information

If you complete six continuous months of GLP-1 injectable treatment as prescribed and haven’t lost weight compared with your logged starting weight, we refund everything you paid us over those six months — medication, consultation fees, and plan fees. There’s nothing to send back.

It’s our commitment that six months of treatment shouldn’t cost you anything if it doesn’t work for you.

It is not a medical guarantee. We’re not promising you’ll lose weight, and individual results vary. Your clinician’s guidance always comes first.

It applies to GLP-1 injectable plans started on or after September 18, 2026.

Read the full terms

Four steps:

1. Complete the intake — 2 to 5 minutes, depending on your health history. Questions about your health, current medications, and goals.
2. A clinician reviews it — typically within 24 hours. They may message you for more detail.
3. If prescribed, the pharmacy prepares your medication — usually 2 to 3 business days.
4. It ships to you — expedited 2-day shipping, free.

You’re only charged after a clinician approves your treatment. A temporary authorization hold appears at checkout and is released if no prescription is written.

See how it works in detail Start your intake

You choose your plan at checkout: monthly, 3-month, or 6-month. You’re only charged after a clinician reviews your information and issues a prescription. A temporary authorization hold appears at checkout and is released by your bank, typically within 3 to 7 business days, if no prescription is written.

Plans renew automatically at the interval you chose until you pause or cancel. We send a reminder before each renewal.