Most Affordable 
Lowers cardiovascular risk 
Decreases cholesterol 
Feel full for longer 
Improves blood sugar Targets your fullness signal
Your brain: “enough” GLP-1 signal Your gut releases GLP-1 after a meal
After you eat, your body releases GLP-1 — a hormone that travels to your brain and says: enough. Semaglutide mimics that signal.
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$125/mo For life
*SEMA 6 month plan 
Most Affordable
In stock
The most studied GLP-1
for weight loss
- Lowers cardiovascular risk
- Decreases cholesterol
- Feel full for longer
- Improves blood sugar
Lose up to 15% of
your weight
GLP-1 (Semaglutide)
A once-weekly injection that activates the hormone receptor your body already uses to regulate hunger — slowing how quickly food leaves your stomach and quieting appetite signals.
GLP-1 is a hormone your body releases after eating. It tells your brain you're full and slows the rate food moves through your stomach — but it clears from your system within minutes. Semaglutide is built to do the same job and stay active far longer, so the fullness signal holds instead of fading between meals.
14.9% Average weight loss with Semaglutide
*New England Journal of Medicine
Slows how fast your stomach empties
hunger returns more slowly
Food leaves your stomach more gradually after a meal, so fullness lasts and hunger returns more slowly.
Steadies the swings that drive cravings
2 h 4 h meal
A steadier pace of digestion means fewer sharp spikes and crashes — the pattern that usually sends you looking for food.
Your price stays flat at every dose level.
Choose planEach dose level lasts at least 4 weeks on the standard schedule. If your provider advances you at every step, a typical month-by-month plan looks like this — though your provider may keep you at any level longer based on how you respond and tolerate it, and many patients stay below the maximum dose.
| Month | Weekly dose | Phase |
|---|---|---|
| Month 1 | 0.25 mg | Starting dose |
| Month 2 | 0.5 mg | Titration |
| Month 3 | 1 mg | Titration |
| Month 4 | 1.5 mg | Titration |
| Month 5+ | 2.5 mg | Maximum dose |
Get incredible results,
“This has been life changing for me. I have been able to stop thyroid and blood pressure medication. I got my confidence back and I can play and run with my kids!
“Since starting my treatment with Yucca Health, I'm most excited to see my clothes fitting better again! I also feel this GLP-1 has helped with my irritability as well.
All plans include
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U.S. Licensed Pharmacies. All 50 states.
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Free provider consultation & injection kit.
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Free shipping. Arrives in 2 days.
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Same price, every dose. For life.
Manage your treatment, anytime, anywhere.
- Stay in touch with doctor
- Track your progress
- Update or change your treatment
All major credit cards accepted:
Buy Now, Pay Later Available
Spread payments over time!
What most patients ask us before starting
GLP-1 treatment is a class of prescription medication — including GLP-1 (Semaglutide) and GLP-1 + GIP (Tirzepatide) — that works with your body's natural appetite signals, helping you feel full sooner, stay satisfied longer, and reduce the constant food noise. At Yucca Health, every protocol is reviewed by a licensed provider and built around you.
Semaglutide is a GLP-1 receptor agonist. Tirzepatide is a dual GIP and GLP-1 receptor agonist. Both are designed to support appetite regulation and long-term weight management, but they work through different receptor pathways. Your provider reviews your health history and goals to determine what may be appropriate for you.
GLP-1 treatment may be considered for adults working toward provider-guided weight management who meet clinical criteria. Eligibility is determined by a licensed provider based on your medical history, current health, and goals. Treatment isn't right for everyone — that's why every plan begins with a provider review, not a checkout.
You complete a quick clinical intake, share your medical history, and connect with a licensed provider. If approved, your medication is prepared by a partner pharmacy and shipped directly. Your provider stays involved as your dosing is titrated and adjusted over time.
Side effects vary by person. Common effects may include nausea, constipation, diarrhea, appetite changes, or digestive discomfort, especially while your body adjusts. Your provider reviews your medical history, explains what to watch for, and can adjust your protocol if needed.
No. Yucca Health provides compounded medications containing the same active pharmaceutical ingredients (APIs) as brand-name drugs. Compounded medications are prepared by licensed U.S. pharmacies, are not FDA-approved, and do not undergo FDA review for safety, effectiveness, or manufacturing quality.
The science of feeling better.
Evidence-based articles on the future of modern telehealth - for your reading pleasure.
Semaglutide Constipation: Why It Happens and 7 Things That Actually Help
Constipated on semaglutide? Discover why it happens and follow a 7-step provider-backed protocol to get relief safely and stay on track.
Can Semaglutide Cause Depression or Mood Changes? What Studies Show
Clinical data shows no causal link between semaglutide and depression. Learn why losing food noise can feel like sadness, and what to do about it.
Semaglutide Maintenance Dose: How to Stay at Your Goal Without Side Effects
Find your ideal semaglutide maintenance dose. Learn how provider-guided tapering protects your results and prevents the GLP-1 rebound effect.
Personalized treatments, built around your goals
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